Notwithstanding different setbacks, several MDM2 inhibitors have now progressed into late-phase scientific advancement. New techniques have also been developed to improve the efficacy of MDM2 inhibitors and also to mitigate their on-target toxicity. During this critique, we summarize the progress and worries in the development of a MDM2 specific therapy. https://dorsomorphin11098.newbigblog.com/37797432/the-basic-principles-of-panobinostat