Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. As opposed to opioids, which bind to µ-opioid receptors in the central nervous procedure, conolidine modulates alternate molecular targets. A Science Innovations examine found that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://cyberbookmarking.com/story20754731/details-fiction-and-conolidin-to-replace-traditional-painkillers